| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Fidelity Management & Research Co. LLC | 4,872,036 | 165,127 | 3,957,554,842.8 | 0.1871 | 7.7877 | 06/30/2026 |
| 2 | Janus Henderson Investors US LLC | 2,415,238 | -78,584 | 1,961,897,827.4 | 0.8697 | 3.8606 | 06/30/2026 |
| 3 | Capital Research & Management Co. (World Investors) | 2,199,770 | -56,446 | 1,786,873,171 | 0.1593 | 3.5162 | 06/30/2026 |
| 4 | T. Rowe Price Associates, Inc. (IM) | 1,959,784 | -617,598 | 1,591,932,543.2 | 0.1723 | 3.1326 | 06/30/2026 |
| 5 | Artisan Partners LP | 1,508,778 | 40,796 | 1,225,580,369.4 | 1.0018 | 2.4117 | 06/30/2026 |
| 6 | Avoro Capital Advisor LLC | 1,000,000 | 0 | 812,300,000 | 8.6852 | 1.5984 | 06/30/2026 |
| 7 | T. Rowe Price International Ltd. | 718,263 | -79,310 | 583,445,034.9 | 0.3073 | 1.1481 | 06/30/2026 |
| 8 | RTW Investments LP | 709,446 | 0 | 576,282,985.8 | 5.381 | 1.134 | 06/30/2026 |
| 9 | Wellington Management Co. LLP | 666,317 | -71,302 | 541,249,299.1 | 0.0869 | 1.0651 | 06/30/2026 |
| 10 | Invesco Advisers, Inc. | 422,199 | -137,911 | 342,952,247.7 | 0.135 | 0.6749 | 06/30/2026 |
| 11 | AllianceBernstein LP | 395,661 | -26,643 | 321,395,430.3 | 0.0913 | 0.6324 | 06/30/2026 |
| 12 | BlackRock Fund Advisors | 371,986 | 28,775 | 302,164,227.8 | 0.0055 | 0.5946 | 06/30/2026 |
| 13 | Bellevue Asset Management AG | 301,000 | -12,000 | 244,502,300 | 4.463 | 0.4811 | 06/30/2026 |
| 14 | Sands Capital Management LLC | 298,599 | -41,686 | 242,551,967.7 | 0.6026 | 0.4773 | 06/30/2026 |
| 15 | Bessemer Investment Management LLC | 267,779 | 203,528 | 217,516,881.7 | 0.2548 | 0.428 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | American Funds EUPAC Fund | 1,024,240 | -72,961 | 831,990,152 | 0.6255 | 1.6372 | 06/30/2026 |
| 2 | Fidelity Growth Company Commingled Pool | 817,584 | 1,112 | 664,123,483.2 | 0.4972 | 1.3069 | 08/31/2026 |
| 3 | American Funds New Economy Fund | 729,820 | 16,126 | 592,832,786 | 1.2398 | 1.1666 | 06/30/2026 |
| 4 | Fidelity Growth Company Fund | 608,314 | -752 | 494,133,462.2 | 0.4869 | 0.9724 | 08/31/2026 |
| 5 | Janus Henderson Forty Fund | 518,956 | -18,917 | 421,547,958.8 | 1.7088 | 0.8295 | 06/30/2026 |
| 6 | Fidelity OTC Portfolio | 472,226 | -12,600 | 383,589,179.8 | 0.7986 | 0.7548 | 08/31/2026 |
| 7 | iShares Biotechnology ETF | 436,887 | 95,004 | 354,883,310.1 | 3.2643 | 0.6983 | 09/30/2026 |
| 8 | St. James's Place Global Growth Unit Trust | 309,191 | 0 | 251,155,849.3 | 1.058 | 0.4942 | 01/31/2026 |
| 9 | Janus Henderson Enterprise Fund | 309,064 | 0 | 251,052,687.2 | 1.1862 | 0.494 | 06/30/2026 |
| 10 | Fidelity Contrafund | 240,515 | 43,785 | 195,370,334.5 | 0.1069 | 0.3844 | 08/31/2026 |
| 11 | T Rowe Price Growth Stock Fund | 225,019 | -46,539 | 182,782,933.7 | 0.3541 | 0.3597 | 06/30/2026 |
| 12 | T. Rowe Price Large Cap Growth Fund | 211,419 | -875 | 171,735,653.7 | 0.7943 | 0.3379 | 06/30/2026 |
| 13 | T. Rowe Price New Horizons Fund | 208,186 | -8,097 | 169,109,487.8 | 1.3132 | 0.3328 | 06/30/2026 |
| 14 | T Rowe Price Overseas Stock Fund | 194,314 | -40,835 | 157,841,262.2 | 0.6422 | 0.3106 | 06/30/2026 |
| 15 | Fidelity Puritan Fund | 182,989 | -43,200 | 148,641,964.7 | 0.6337 | 0.2925 | 08/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Bessemer Investment Management LLC | 267,779 | 203,528 | 217,516,881.7 | 0.2548 | 0.428 | 06/30/2026 |
| 2 | Fidelity Management & Research Co. LLC | 4,872,036 | 165,127 | 3,957,554,842.8 | 0.1871 | 7.7877 | 06/30/2026 |
| 3 | Barclays Bank Plc (Private Banking) | 134,427 | 129,152 | 109,195,052.1 | 0.0582 | 0.2149 | 06/30/2026 |
| 4 | Capital Research & Management Co. (Global Investors) | 88,511 | 88,511 | 71,897,485.3 | 0.0089 | 0.1415 | 06/30/2026 |
| 5 | Bank of America, NA (Private Banking) | 116,549 | 80,615 | 94,672,752.7 | 0.0243 | 0.1863 | 06/30/2026 |
| 6 | Two Sigma Investments LP | 185,638 | 76,517 | 150,793,747.4 | 0.115 | 0.2967 | 06/30/2026 |
| 7 | 1832 Asset Management LP | 157,940 | 73,740 | 128,294,662 | 0.1046 | 0.2525 | 06/30/2026 |
| 8 | Canada Pension Plan Investment Board | 60,577 | 60,577 | 49,206,697.1 | 0.0186 | 0.0968 | 06/30/2026 |
| 9 | Westfield Capital Management Co. LP | 57,082 | 57,082 | 46,367,708.6 | 0.1584 | 0.0912 | 06/30/2026 |
| 10 | Morgan Stanley & Co. LLC | 160,006 | 57,037 | 129,972,873.8 | 0.0378 | 0.2558 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. (IM) | 1,959,784 | -617,598 | 1,591,932,543.2 | 0.1723 | 3.1326 | 06/30/2026 |
| 2 | Invesco Advisers, Inc. | 422,199 | -137,911 | 342,952,247.7 | 0.135 | 0.6749 | 06/30/2026 |
| 3 | T. Rowe Price International Ltd. | 718,263 | -79,310 | 583,445,034.9 | 0.3073 | 1.1481 | 06/30/2026 |
| 4 | Janus Henderson Investors US LLC | 2,415,238 | -78,584 | 1,961,897,827.4 | 0.8697 | 3.8606 | 06/30/2026 |
| 5 | Wellington Management Co. LLP | 666,317 | -71,302 | 541,249,299.1 | 0.0869 | 1.0651 | 06/30/2026 |
| 6 | Fiera Capital Corp. (Investment Management) | 26,546 | -70,955 | 21,563,315.8 | 0.0785 | 0.0424 | 06/30/2026 |
| 7 | Braidwell LP | 17,707 | -67,232 | 14,383,396.1 | 0.5082 | 0.0283 | 06/30/2026 |
| 8 | Goldman Sachs & Co. LLC (Private Banking) | 53,512 | -58,906 | 43,467,797.6 | 0.0111 | 0.0855 | 06/30/2026 |
| 9 | Capital Research & Management Co. (World Investors) | 2,199,770 | -56,446 | 1,786,873,171 | 0.1593 | 3.5162 | 06/30/2026 |
| 10 | TD Asset Management, Inc. | 24,675 | -56,149 | 20,043,502.5 | 0.0094 | 0.0394 | 06/30/2026 |
Data provided by FactSet Research Systems Inc.